Next Generation Sequence Assembly with AMOS.

Title	Next Generation Sequence Assembly with AMOS.
Publication Type	Journal Article
Year of Publication	2011
Authors	Treangen TJ, Sommer DD, Angly FE, Koren S, Pop M
Journal	Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.]
Volume	Chapter 11
Pagination	Unit11.8
Date Published	2011 Mar
ISSN	1934-340X
Abstract	A Modular Open-Source Assembler (AMOS) was designed to offer a modular approach to genome assembly. AMOS includes a wide range of tools for assembly, including the lightweight de novo assemblers Minimus and Minimo, and Bambus 2, a robust scaffolder able to handle metagenomic and polymorphic data. This protocol describes how to configure and use AMOS for the assembly of Next Generation sequence data. Additionally, we provide three tutorial examples that include bacterial, viral, and metagenomic datasets with specific tips for improving assembly quality.Curr. Protoc. Bioinform. 33:11.8.1-11.8.18. © 2011 by John Wiley & Sons, Inc.

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